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Ivf vs ivi4/29/2023 ![]() ![]() When sperm is found and ICSI is used, 36% of these IVF cycles lead to a live birth. Often just a little sperm is retrieved, so fertilizing the eggs with Conventional Insemination isn’t an option. These men produce no sperm and surgery is required to retrieve it from nodules in the testicle. ![]() Let’s look at the case of men with non-obstructive azoospermia (known as NOA). ![]() 34%) Severe Male Factorįor men who produce no sperm (known as “ azoospermia”) or sperm that doesn’t swim forward, ICSI clearly improves the odds a cycle will result in a baby and should be considered a requirement. 14%) and yet this translated into only moderately higher live birth rates per cycle (37% vs. When the CDC reviewed how all male factor patients fared with ICSI versus CI, cycles that used ICSI were less likely to be canceled (6% vs. Morphology: Less than 4 - 5% of sperm are of the proper shape.Motility: Less than 40% of sperm are able to swim forward.Concentration: The volume of sperm produced per milliliter is below 15 million.How does a man know if he has a male factor issue? Below are the components of the semen analysis and cut-offs for each parameter that may indicate a man has a male factor issue. On the other hand, there’s very little data that shows using ICSI improves success rates for patients with “mild” or “moderate” male factor infertility, which encompasses most male factor patients. ICSI was developed to treat severe forms of male factor infertility and in these cases ICSI is necessary and effective. Below is a quick summary of what the data reveals. The reality is that a minority of these patients likely benefit from ICSI and in this section we’ll cover where the data supports one approach versus another. Today ICSI is used in 90% of IVF cases that involve male factor and 60% of cases that don’t. The chief issue with ICSI is that this microsurgery costs an additional $1,500 - $3,000, can only be performed on “mature eggs” (ruling out ~20% of eggs that are retrieved), 5 - 15% of eggs are damaged in the process, success rates vary by embryologist, and there is some suggestion the offspring from ICSI may fare slightly worse. In this technique an embryologist selects a single sperm from a man’s semen sample and injects it directly into the egg. That seldom happens with CI’s alternative, ICSI. The fear with CI is that in 10 - 15% of cases, patients experience total fertilization failure (TFF) where none of their eggs fertilize. Conventional insemination largely recreates the “best sperm wins” dynamic of natural conception. In this technique, a woman’s eggs are surrounded by sperm in a petri-dish and ultimately one sperm fertilizes the egg. There are effectively two techniques used to fertilize eggs during IVF: conventional insemination (CI) or intra-cytoplasmic sperm injection (ICSI). ![]()
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